| abstract |
The subject-matter of the invention are 3(2H)-Pyridazinone derivatives of the general formulan wherein nR stands for an ethyl or propyl group substituted by a terminal halogen atom or hydroxyl group or a terminal group of the formulan in which latter nR₁ represents a hydrogen atom or an optionally substituted benzyl group and nR₂ represents a hydrogen atom or an optionally substituted benzo[1,4]dioxan-2-yl-methyl or benzo[1,4]dioxan-2-yl-ethyl group or a group of the formulan in which latter nn is 2 or 3 and nR₃ stands for an optionally substituted phenoxy or phenylthio group and nX stands for a hydrogen or halogen atom or an optionally substituted saturated or unsaturated 5- or 6-membered heterocyclic group. n Furthermore the subject-matter of the invention are a process and intermediates for preparing these compounds and medicaments containing them and/or other 3(2H)-pyridazinone derivatives. n The compounds according to the invention inhibit the adrenergic alpha₁ receptors, have a calcium-antagonistic effect and exert blood pressure lowering action. |