Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
1986-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_152d429d079ab74fea07349b988ebb29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e055aecfc2b555af0ba914d53cbd7f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9ff0256793c8fef56f03fb763afd683 |
publicationDate |
1987-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0218474-A2 |
titleOfInvention |
Novel DNA and polypeptide |
abstract |
This invention relates to a polypeptide exhibiting hepatitis B virus e antigenicity produced by a microorganism; a recombinant DNA comprising a DNA fragment coding for a polypeptide exhibiting hepatitis B virus e antigenicity; a recombinant DNA comprising a DNA fragment coding for a polypeptide exhibiting hepatitis B virus c antigenicity, wherein the nucleotide sequence between the SD sequence of the promoter and the translational initiation codon is ATCGGGC; and a method of preparing polypeptides exhibiting hepatitis B virus e and c antigenicity respectively, which comprises cultivating transformants containing above-described recombinant DNAs respectively. n The thus obtained polypeptide exhibiting HBc or HBe antigenicity may be used as a diagnostic reagent for HBV infection and a defensive (preventing) agent against HBV infection. n A recombinant DNA having a base sequence of ATCGGGC between the SD sequence of its promoter region and the translational initiation codon affords a gene product having HBc or HBe antigenicity with a high yield and is advantageously used for the production of HBc or HBe antigen. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0272483-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6072049-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6589530-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2162894-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6100065-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6117653-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6110706-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9424864-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0299242-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6020167-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8810300-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0299242-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5610050-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6022543-A |
priorityDate |
1985-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |