abstract |
Method of blocking 5HT 2 without effect on alpha receptors with 1-loweralkyl-6-straight chain alkyl-8β-hydroxycyclo- alkyloxycarbonylergolines of the formulan wherein R is primary or secondary C 1 -C 8 alkyl, CH 2 C 2 -C 4 alkenyl, C 3 -C 8 cycloalkyl or C 3 -C 6 cycloalkyl-substituted C 1 -C 5 primary or secondary alkyl, the total number of carbon atoms in R not to exceed 8; R 1 is C 1 -C 4 straight chain alkyl or allyl, and R 2 is hydroxy C 5 -C 7 cycloalkyl, or a pharmaceutically-acceptable salt thereof. |