| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef1a63d62269b5b64f99ee8720351481 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
1986-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebdfc9964130338e8db2015194a5d68b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d1317702fb04b22ea0d4538416e07fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e73aff1c749be831f200e19af0bd4c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e6854fe6a2e64354907285fea16c183 |
| publicationDate |
1987-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0213175-A1 |
| titleOfInvention |
CYSTEIN REDUCED MUTEINE FROM BIOLOGICALLY ACTIVE HUMAN TNF PROTEINS. |
| abstract |
Synthetic muteins of the biologically active human tumor necrotic factor (hTNF) where at least one of the two cysteine residues is deleted or replaced by another amino acid to eliminate intermolecular crosslinking sites. The invention also relates to the synthetic structural genes having DNA sequences designed specifically for the coding of the synthetic hTNF muteins described above. |
| priorityDate |
1985-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |