http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0212550-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D335-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D335-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 |
| filingDate | 1986-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1989-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0212550-A3 |
| titleOfInvention | Substituted dipeptide amides |
| abstract | The invention relates to novel substituted tyrosyl alanine ndipeptide amides of the formula: n nand the pharmaceutically acceptable acid addition salts thereof nwherein R¹ is hydrogen, lower alkyl, hydroxy, lower alkoxy, n-O(CH₂) n phenyl with the phenyl optionally substituted by nhalogen, -NO₂, -CN, -NH₂ or lower alkyl wherein n is 1 to n4; R² and R³ represent lower alkyl, halogen, or lower nalkoxy, or either one of R² or R³ is hydrogen and the other nis lower alkyl, lower alkoxy or halogen; R⁴, R⁵, R⁶, and nR⁹ may be the same or different and represent hydrogen, lower nalkyl, cycloalkyl having 3 to 8 carbons, unsaturated lower nalkyl, or -(CH₂) m cycloalkyl with the cycloalkyl having 3 to n8 carbons and m is 1 to 4; R 10 is hydrogen or n-(CH₂) p phenyl or with the phenyl optionally substituted n n nwith -NH₂, -OH, halogen, -NO₂, or lower alkyl or n-(CH₂) p thienyl wherein p is 1 to 4; one of R⁷ or R⁸ is n-(CH₂) f -S(O) z -(CH₂) q -CH₃ where f is 1 to 3 and q is n0 to 3, z is 0, 1 or 2 and the other is hydrogen or lower nalkyl, or R⁷ and R⁸ together with carbon w is n nwhere x and y are independently 1 to 3 and z is 0, or 2. nV represents an asymmetric carbon that may be recemic or have nthe D or L configuration; W represents an asymmetric carbon nwhen R⁷ and R⁸ are not the same that may be recemic or have nthe D or L configuration. nThe compounds of this invention are useful as analgesic and/or nantihypertensive agents. |
| priorityDate | 1985-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.