| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-46 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-735
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-04 |
| filingDate |
1986-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1992-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1992-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0211037-B1 |
| titleOfInvention |
METHOD OF PRODUCING HIGH MOLECULAR WEIGHT SODIUM HYALURONATE BY FERMENTATION OF $i(STREPTOCOCCUS) |
| abstract |
A composition of sodium hyaluronate is provided having no skin irritation and no pyrogenicity and inflammatory activity. Such a composition can be obtained by a novel mutant microorganism Streptococcus zooepidemicus HA-116 ATCC 39920. Said strain produces large amounts of high molecular weight hyaluronic acid that is excreted into the medium by the organism when the medium includes a sugar component as the carbon source in a substantially constant concentration between 0.2 and 10 g per literat a pH of 6.5 to 7.5 together with a substantially constant magnesium ion concentration that is above 0.05 g per liter. |
| priorityDate |
1985-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |