http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0210279-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6462 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 |
| filingDate | 1986-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1991-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0210279-B1 |
| titleOfInvention | Stabilized human prourokinase |
| abstract | Stabilized human prourokinase-like polypeptides wherein the 135th lysine from the N-terminal of human prourokinase is substituted by an amino acid other than basic amino acids, the 157th phenylalanine is substituted by an acidic amino acid, or both of the amino acids are substituted as described above; DNA segment which codes said polypeptides; plasmid which contains said DNA segment; E. coli transformed by said plasmid; and a process for preparing said polypeptide by using said E. coli. The polypeptides are stable against proteases such as plasmin, thrombin, trypsin, etc., thus being easily purified and collected in a pure form. When applied to a living body, the polypeptides are expected to provide a persistent fibrinolytic activity. |
| priorityDate | 1985-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.