| abstract |
Ambroxol or bromhexine or their salt-containing drug granules with delayed release of active ingredient for oral use and a process for its preparation are described. The pharmaceutical granules contain a) 1 part by weight of the active ingredients which are soluble in gastric juice and sparingly soluble in intestinal juice, ambroxol or bromhexine or their salts, b) 0.2 to 10 parts by weight, preferably 0.5-5, of a low-melting lipid with a melting range of 40 - 90 ° C, preferably 55 - 75 ° C, c) 0.2 to 10 parts by weight, preferably 0.5 - 5, of a gastric juice-insoluble, intestinal juice-soluble film former in powder form, d) optionally other conventional formulation auxiliaries, all of which Components are present as a mixture. |