| abstract |
A packing material for liquid chromatography, comprising particles having a silicone polymer film coated on substantially the entire surface thereof, the packing material being produced by a process comprising the steps of:(a) bringing at least one silicone compound having the general formula (I):wherein R<sup>1</sup>, R<sup>2</sup>, and R<sup>3</sup> represent, independently, a hydrocarbon residue having 1 to 10 carbon atoms, which may be substituted with at least one halogen atom, R<sup>4</sup>, R<sup>5</sup>, and R<sup>6</sup> represent, independently, hydrogen ora hydrocarbon residue having 1 to 10 carbon atoms, which may be substituted with at least one halogen atom, a is zero or an integer of 1 or more, b is zero or an integer of 1 or more, c is zero or 2, and a + b + c is 3 to 300, into contact with particles, whereby the silicone compound is polymerized on substantially the entire surface of the particles, and(b) crosslinking unreacted Si-H groups in the presence of a catalyst, or(c) carrying out an addition reaction of a vinyl compound having up to 40 carbon atoms to unreacted Si-H groups. |