| abstract |
1,2,3,5-Tetrahydroimidazo[2,1-b]quinazolin-2-(1H)-one cardiac stimulants, and their pharmaceutically acceptable salts, of the formula:- n<CHEM>n or a pharmaceutically acceptable salt thereof, whereinn "Het" is an optionally substituted 5- or 6-membered aromatic heterocyclic group attached to the 6-, 7-, 8-, or 9-position of saidn 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-(1H)-one;n R, which is attached to the 6-, 7-, 8-, or 9-position, is hydrogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, hydroxymethyl, halo or CF3; andn R<1>, R<2>, R<3>, R<4> and R<5> are each H or C1-C4 alkyl. |