| abstract |
New fluorinated 1- (α-phenylalkyl) -1H-1,2,3-triazole compounds of the formula; <IMAGE> wherein Ph is a phenyl radical substituted in the o-position by fluorine and optionally additionally by at least one further halogen atom, alk is lower alkylidene, R1 is hydrogen, lower alkyl or an unsubstituted or substituted by lower alkanoyl or lower alkyl and R2 is an unsubstituted or by Lower alkanoyl or lower alkyl substituted carbamyl group has anticonvulsant properties and can be used as medicaments. They are prepared by reacting a compound of the formula <IMAGE> in which Y4 is esterified carboxy and Y5 is hydrogen, lower alkyl or likewise esterified carboxy, with an excess of ammonia or a di-lower alkylamine and, if desired, a compound obtainable according to the process, in which R2 and optionally R1 unsubstituted carbamyl means R2 and optionally R1 lower alkanoylated. |