http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0197478-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
filingDate | 1986-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1990-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1990-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0197478-B1 |
titleOfInvention | Diphosphonic-acid derivatives, process for preparing them and medicines containing these compounds |
abstract | The present invention provides diphosphonic acid derivatives of the general formula: <IMAGE> (I) wherein R1, R2, R3, R4 and R5, independently of one another or also together, signify hydrogen atoms or lower alkyl radicals, whereby R1 and X or R3 and Y or R4 and Z, together with the nitrogen atom to which they are attached, can form a five- or six-membered ring, X and Y, which can be the same or different, represent a straight-chained or branched alkylene chain with up to 6 carbon atoms which can optionally be substituted by aromatic or heteroaromatic radicals, Z is a straight-chained or branched alkylene chain with up to 6 carbon atoms, which can be interrupted by heteroatoms and can optionally also be substituted by aromatic or heteroaromatic radicals, n is 0, 1 or 2 and A is a hydrogen atom or a hydroxyl group, and the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these new diphosphonic acid derivatives and pharmaceutical compositions containing them for the treatment of calcium metabolism disturbances. |
priorityDate | 1985-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.