http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0195496-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-04 |
| filingDate | 1986-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1990-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0195496-A3 |
| titleOfInvention | Use of xanthines in the treatment of proliferative skin disease |
| abstract | 1. A method for the treatment of proliferative skin ndisease in human or non-human mammals which comprises nadministering to the human or non-human mammal in need nof such treatment an effective non-toxic amount of a ncompound of formula (I): n nwherein R¹ and R², which may be the same or different, neach represents a straight-chain or branched-chain alkylrandical of 2 to 6 carbon atoms, or a cyclohexyl, alkoxyalkyl or nhydroxyalkyl radical, and X represents a hydrocarbon radical nhaving up to 4 carbon atoms which may be substituted by a nmethyl group; na compound of formula (II): n nwherein nX² is sulphur and Y is oxygen or sulphur: nR⁴ is an alkyl group of up to 6 carbon atoms; nR⁵ is an alkyl group of up to 6 carbon atoms; and m is 1; nor nX² is oxygen and Y is sulphur; one of R⁴ and R⁵ is an nalkyl group of up to 6 carbon atoms and the other is an alkyl ngroup of 2 to 3 carbon atoms; and m is 1 or 2; na compound of formula (III): n nwherein nR⁶ is a lower alkyl group and R⁷ is a lower alkyl group; or nR⁶ is linked to R⁷ so that the OR⁶ and OR⁷ moieties and the ncarbon atom to which they are attached form a 1,3-ndioxacyclohexa -2,2-diyl, 1,3-dioxacyclopenta -2,2-diyl or n1,3-dioxacyclohepta-2,2-diyl diradiacal; and R⁸ and R⁹ are the nsame or different and are each a lower alkyl group; na compound of formula (IV): n nwherein R¹⁰ is a lower alkyl group and R¹¹ is a lower alkyl ngroup optionally linked to R¹⁰ so that the OR¹⁰ and OR¹¹ nmoieties and the carbon atom to which they are attached nform a 1,3-dioxacyclohexa-2,2-diyl, 1,3-dioxacyclo-penta-2,2-ndiyl or 1,3-dioxacyclohepta-2,2-diyl diradical; or na compound of formula (V): n nwherein R¹² is C₁-₄ alkyl. |
| priorityDate | 1985-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.