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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04
filingDate 1986-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1991-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0194846-B1
titleOfInvention Preparation of thieno-imidazole derivatives
abstract A process for the preparation of a thieno-imidazole derivative having the general formula:-werein R is -(CH<sub>2</sub>)<sub>4</sub>CH<sub>3</sub>, -(CH<sub>2</sub>)<sub>3</sub>OR<sup>1</sup> or -(CH<sub>2</sub>)<sub>5</sub>0R<sup>1</sup>, R' is (C<sub>1</sub>-C<sub>6</sub>) alkyl, -(CH<sub>2</sub>)<sub>4</sub>CN or -(CH<sub>2</sub>)<sub>4</sub>COOR<sup>2</sup> and R<sup>2</sup> is (C<sub>1</sub>-C<sub>6</sub>) alkyl or phenyl; characterized in that a compound of the formula:-wherein R is as defined above, is reacted with an epoxy compound of the formula:-wherein R<sup>3</sup> is hydrogen, methyl or-CH<sub>2</sub>OH; in the presence of an alkanol.In particular this process may be used to prepare descarboxybiotin which is a useful intermediate for the preparation of d - biotin.
priorityDate 1985-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 46.