| abstract |
Compounds of formula (I):in whichRi is hydrogen or C<sub>1-6</sub> alkyl;R<sub>2</sub> is hydrogen or a group -C0<sub>2</sub>R<sub>3</sub> where R<sub>3</sub> is hydrogen or C<sub>1</sub>-<sub>6</sub> alkyl;n is an integer of from 2 to 12;X represents a double or triple bond, and each of A and B represents hydrogen when X is a double bond, or both A and B are absent when X is a triple bond; and represents an aromatic heterocyclic ring, are disclosed as inhibitors of 5-lipoxygenase. |