http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0186347-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-811 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 |
filingDate | 1985-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0186347-B1 |
titleOfInvention | Method for producing high-active biologically efficient compounds immobilized on a carrier |
abstract | The principles of invention consists in a two-step process of immobilization of biologically efficient compounds where the biologically efficient compounds are bonded to a macroporous polymeric carrier containing reactive functional groups from an aqueous solution by a hydrolytically stable linkage. The process is characterized in the first step by a hydrophobic adsorption of the biologically efficient compounds on a macroporous matrix of the carrier and to an increase of their concentration on the solid surface. In the second step, the reaction takes place with the reactive functional groups of carrier and a covalent linkage is formed. The hydrophobic adsorption of compounds determined for immobilization is achieved by addition of inorganic salts in concentration 0.5 to 3.0 mol/1. n<??>The invention can be utilized in the preparation of enzymatic catalysts for transformations of compounds and in the preparation of specific sorbents for both the analytical and preparative affinity chromatography. These methods are used in biotechnology, chemical and clinical analysis, food industry, pharmacology and clinical therapy. |
priorityDate | 1984-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.