abstract |
This invention relates to novel organic trithio oxides of the formula: R<sup>1</sup>-X-R-X<sup>1</sup>-R<sup>1</sup> wherein R is selected fromX is selected fromX' is selected from -S-S-,and each R' is independently selected from carboxyalkyl, alkoxy, alkylthio, amino, alkylamino and acyl substituted and unsubstituted lower alkyl, lower alkenyl, lower alkynyl, phenyl and lower alkylphenyl; provided when R isthen R<sup>1</sup> is not in both instances -CH<sub>2</sub>CH=CH<sub>2</sub>.This invention also relates to a method of preparing the above-identified compounds by heating and further oxidiz- ing various oxides of organic disulfides and to antithrombotic uses of the compounds. |