http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0177610-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-582 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-58 |
| filingDate | 1985-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_533e0e7c2b9ebca07d5be6f185d29060 |
| publicationDate | 1986-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0177610-A1 |
| titleOfInvention | Atrial peptide analogs |
| abstract | Atrial peptide analogues of formula (I) where R1 represents Ser or D-Ser; R4 represents Phe or desR4; R5 represents Gly or desR5; R6 represents Gly or desR6; R8 represents Met, Nle, Nva or Ile; R12 represents Gly or D-Ala; R16 represents Gly or desR16; R17 represents Leu or desR17; R18 represents GLy or desR18; R22 represents Phe or desR22; R23 represents Arg, Arg-Tyr or desR23; Q represents S or CH2; Q 'represents S or CH2 and Y represents OH or NHR, where R represents H or lower alkyl. Either a D-isomer residue is present, or Q or Q 'represents CH2, or one or more of the residues in positions 4-6 and 16-18 are deleted. These analogs or their pharmaceutically acceptable salts, dispersed in a pharmaceutically acceptable liquid or a solid carrier, can be administered to mammals for their natriuretic and diuretic activity, to relieve hypertension or to counteract a congestive heart failure. |
| priorityDate | 1984-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 161.