abstract |
The platelet activating factor (acetylglyceryl ester phosphorylcholine, PAF) is known as a potent lipid mediator, which is released by animal and human pro-inflammatory cells.n n n The invention relates to PAF-antagonistic pharmaceutical compositions which contain as active ingredient one or more diazepines of the general formulas I and II according to claim 1.n n n These pharmaceutical compositions are used to treat pathological conditions and diseases in which PAF is involved. |