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filingDate 1985-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1991-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0175721-B1
titleOfInvention Method and apparatus for the separation of components of a mixture by thin layer chromatography
abstract The method and plant disclosed combine the advantages of the preparatory centrifugal stratification chromatography, of the analytical horizontal, anticircular and sequential thin layer chromatography. In this new on-line preparatory method the addition of solvent may be varied in parallel, locally and temporally. It is thus possible to improve sections of the integral chromatogram in their separation by selecting for these partial problems the optimum composition of the solvent. The separations are basically obtained in two different ways: 1. The circular separations are effected by means of the centrifugal force by using a sequential solvent supply (20), the separation taking place from the inside to the outside. The separated substances may be brought back to the inner part of the layer by recycling. 2. The anticircular separations are performed by means of the capillary force by using an annular-shaped solvent supply (19), the substance zones being concentrated and/or developed from the outside to the inside. The possibilities of circular and anticircular applications may be combined as desired so that the separation path may be prolonged practically in an illimited manner and thus the capacity and separation power may be considerably increased.
priorityDate 1984-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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