| abstract |
Novel pyrimidones of the formula I and salts thereof are ngastric acid secretion inhibitors and some have other medical nutility: n nwherein R₁ represents a hydrogen atom, a C₁ to C₁₀ alkyl group, a nC₁ to C₅ alkenyl group, a C₁ to C₅ alkinyl group, a phenyl group, a ncycloalkylmethyl group, or an unsubstituted or substituted aralkyl ngroup; R₂ represents a hydrogen atom, a C₁ to C₅ alkyl group or a ntrifluoromethyl group; Y represents a heterocyclic group of the nformula: n nwherein R represents a hydrogen atom or a C₁ to C₅ alkyl group; B nrepresents an oxygen atom or a sulfur atom: m represents zero or nan integer of 1 to 3; and n represents an integer of 1 to 3. Methods nand novel intermediates for their preparation are disclosed, as nwell as medicaments containing them and medical treatments nusing them. |