http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0172821-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b460b6e95e64228f98a7ffc6bde16de |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D419-12 |
| filingDate | 1984-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c45f9c3da0ef86b50db79e670c6a5f65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96ab3f6f8548ea1737c7d59d6d31f155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fab96a8434bf6011d1e73bf0dfcf7df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_272b00b4c0545a33b3691f9f707fed5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_067c55aa2172e4830cdf8c8a058c8230 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c328f276860b1a7796905745f5571752 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_207629915c18fde6a3281f6834de00db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c741144e08108b0aac6877cd5715e36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbcfb4e12b952b896112272bbf5a1f17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d73496239853774bec06b4b61bec7f0c |
| publicationDate | 1986-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0172821-A1 |
| titleOfInvention | NEW OCTAHYDROBENZO (f) QUINOLINE DERIVATIVES. |
| abstract | Compounds corresponding to formulas (I), where C1 and N4 are in transconfiguration with respect to each other, Y represents OH, R1COO, R2R3NCOO- or R4O, R1 being an aliphatic hydrocarbon residue containing from 1 to 17 atoms carbon, phenyl, 2,6-dimethylphenyl or a 3- or 4-hydroxyphenyl group or a 3- or 4-alkanoyloxyphenyl group of formula (II), in which R5 is an alkyl group having from 1 to 6 carbon atoms, or R1 is a group represented by the formula (III), where R6 represents hydrogen, an alkyl group containing from 1 to 5 carbon atoms or a phenyl group, R7 represents hydrogen, a group alkyl having from 1 to 5 carbon atoms or an acyl group and R8 represents hydrogen or an alkyl group having from 1 to 5 carbon atoms, R2 represents hydrogen, an alkyl group having from 1 to 5 carbon atoms carbon, a phenetyl, benzyl or phenyl group which can be mono- or bisubstituted in its aromatic part with a g methyl group, metoxy, hydroxy, nitro or cyano or a halogen, R3 represents H, an alkyl group containing from 1 to 5 carbon atoms or a phenyl group, or R2 and R3, in combination with the nitrogen atom form a ring with 5.6 or 7 members which may contain from 1 to 3 double bonds and / or 1 or 2 additional hetero atoms selected from N, O and S, and R4 represents an allyl or benzyl group and R represents hydrogen or the group (IV), where n is 3 or 4 and R9 represents hydrogen, an alkanoyl group containing from 2 to 6 carbon atoms or benzoyl. These products are used as bases, as well as their pharmaceutically acceptable acid addition salts. Their methods of preparation are also described, as are pharmaceutical preparations and methods of treatment using such compounds. These are useful in the treatment of disorders of the central nervous system. |
| priorityDate | 1983-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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