| abstract |
A modified polypeptide material comprising an insoluble polypeptide carrier and synthetic polymer, the synthetic polymer made from (a) a polymerizable compound which has a chemical group capable of covalent coupling to the insoluble polypeptide carrier and (b) one or more polymerizable compounds containing an ionizable checmical group, a chemical group capable of transformation to an ionizable chemical group, a group capable of causing the covalent coupling of the synthetic polymer to an affinity ligand or a biologically active molecule, or a hydrophobic chemical group. The synthetic polymer is covalently bonded to the insoluble polypeptide carrier. |