abstract |
The invention concerns the novel cyclic amide 1 min -(4-bromo-2-fluorobenzyl)-7 min -chloro-spiro[pyrrolidine-3,3 min -indolin e]-2,2 min ,5-trione in laevorotatory optically active form, its salts, pharmaceutical compositions and methods of manufacture. The novel cyclic amide is of value in the treatment or prophylaxis of various complications of diabetes and galactosemia. |