| abstract |
The intention relates to muramylpeptide derivatives resulting essentially from conjugation or coupling, if necessary by means of an arm, between a muramylpeptide and a group containing two atoms contiguous to each other on each of which is connected a lipophilic chain comprising from 8 to 100 carbon atoms, preferably from 14 to 24 carbon atoms. The derivatives according to the invention are endowed with remarkable stimulating properties with regard to the activation of macrophages, the tumoricidal properties of which they amplify. |