http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0159565-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-23 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
filingDate | 1985-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1284ca18c29b74ff54791d9a783455ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c669d88fc3c869ad054420d7d01162b7 |
publicationDate | 1985-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0159565-A1 |
titleOfInvention | Substituted 2,3,3alpha,6-tetrahydro-6-oxabenzofuran derivatives useful as paf antagonists |
abstract | Substituted 2,3,3α,6-tetrahydro-6-oxabenzofuran deriva- t i ves of formula:n have been prepared whereinn R 1 is (1) when it is joined to the ring by a double bond, e.g., O or S; or (2) when it is joined to the ring by a single bond, e.g., SR 5 where R 5 represents, e.g., H or loweralkyl; R 2 is, eg., loweralkyl; R 3 is, e.g., OR S where R 5 is as previously defined except that it cannot be CH 3 ; R 4 is, e.g., loweralkyl; X is, e.g., H or loweralkyl; and n is, e.g., 2. n These neolignan compounds are found to have potent and specific PAF (Platelet-Activating-Factor) antagonistic activities and thereby useful in the treatment of various diseases or disorders mediated by the PAF, for example, pain, fever, inflammation, cardiovascular disorder, asthma, lung edema, allergic disorders, skin diseases, psoriasis, and adult respiratory distress syndrome. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004080379-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004080379-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2851919-A1 |
priorityDate | 1984-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.