| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-10 |
| filingDate |
1985-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da5707ef55700fa84813f5f3e8df243 |
| publicationDate |
1985-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0156644-A1 |
| titleOfInvention |
Process and intermediates for 4-acetylimidazoles |
| abstract |
This invention provides a two-step process for the preparation of 4-acetylimidazoles. In the first step, a 4-acylamino-5-methylisoxazole is subjected to catalytic hydrogenolysis to give a 4-amino-3-acyl-amino-3-buten-2-one. In the second step, the intermediate 3-buten-2-one compound is cyclized to a 4-acetylimidazole by treatment with a basic agent. The 4-acetylimidazoles are chemical intermediates for preparing known antisecretory agents and histamine H 2 antagonists, useful for the treatment of gastric hyperacidity and peptic ulcers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0332075-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4924000-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2483116-C1 |
| priorityDate |
1984-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |