http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0156611-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-937 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-937 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
filingDate | 1985-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1988-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1988-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0156611-B1 |
titleOfInvention | Intermediates for the preparation of prostaglandin analogues |
abstract | The present invention relates to intermediates of the general formula:(wherein Y and Z, which may be the same or different, each represents a trans-vinylene group or an ethylene group, R<sup>2</sup> represents a hydrogen atom or a methyl or ethyl group, R<sup>3</sup> represents a single bond or an alkylene group of 1 to 5 carbon atoms, R' represents an alkyl group of 1 to 8 carbon atoms, a cycloalkyl group of 4 to 7 carbon atoms unsubstituted or substituted by at least one alkyl group of 1 to 8 carbon atoms or a phenyl or phenoxy group unsubstituted or substituted by at least one halogen atom, trifluoromethyl group of alkyl group of 1 to 4 carbon atoms, R<sup>5</sup> represents a hydroxy- protecting group which can be removed in acidic conditions and W<sup>1</sup> represents a group of the formula : -COOR<sup>1</sup>, -CON(R<sup>6</sup>)<sub>2</sub>, -CH<sub>2</sub>OR<sup>5</sup> or -CH(OR<sup>7</sup>)CH<sub>2</sub>OR<sup>5</sup> (in which R' represents a hydrogen atom or an alkyl group of 1 to 12 carbon atoms, the groups R<sup>6</sup>, which may be the same or different, each represents an alkyl group of 1 to 4 carbon atoms, a phenyl group or an aralkyl group of 7 to 12 carbon atoms or R<sup>7</sup> represents an acyl group of 2 to 12 carbon atoms and R<sup>5 </sup>is as hereinbefore defined) with the proviso that, when R<sup>3</sup> represents a single bond, R<sup>4</sup> does not represent a substituted or unsubstituted phenoxy group, which are useful in the preparation of 6-keto-prostaglandin derivatives. |
priorityDate | 1984-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.