| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_983fa366d54b080542742d72951c002c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-963 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-535 |
| filingDate |
1984-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce9b4510144dc3ecd1eaa49fd29bb9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46521a23e151dc9613f4dcf611e56c0d |
| publicationDate |
1985-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0144176-A2 |
| titleOfInvention |
Method of measuring a biological ligand |
| abstract |
A method of determining a biological ligand which is highly sensitive and specific and which is suitable for use as a clinical test for the determination of physiological substances and trace components in humoral fluid comprises allowing there to coexist in an aqueous medium a system comprising (A) a ligand (1) to be measured, (8) either a combination (1) of an antibody against the ligand (1) and an enzyme capable of acting on a water-insoluble macromolecular substance or a combination (2) of a said enzyme and a ligand (2) having an antigenic determinant which is an antigenic determinant of said ligand (1), which combination (2) is present in the aqueous medium together with a said antibody, and (C) a said macromolecular substance, determining the residual activity of the enzyme after it has acted on said macromolecular substance and utilising the measurement thereby obtained as a measure of the biological ligand. The inventive method makes use of the steric hindrance of the combination (1) or (2) for the enzyme reaction which is carried out at the boundary between solid phase and liquid phase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5179000-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0328664-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0328664-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0152305-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0152305-A3 |
| priorityDate |
1983-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |