| abstract |
Compounds of the formulan wherein R, is cyclopropylmethyl, 2-phenylethyl, aminoalkyl, cycloaminoalkyl, optionally ring-substituted phenoxyalkyl, optionally ring-substituted phenylthioalkyl, optionally ring-substituted phenylsulphinylalkyl, optionally ring-substituted phenylsulphonylalkyl, cycloalkoxyalkyl, optionally ring-substituted phenylalkyl, hydroxyalkyl, alkoxyalkyl or phthali- midoalkyl; R 2 is H, alkyl or phenyl; and Y, is H, CI, Br, F, MO 2 or CF 3 , can have utility as inhibitors of phospholipase A 2 and thus as inhibitors of arachidonic acid cascade biosynthesis. |