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filingDate 1984-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1986-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0138855-A4
titleOfInvention METHOD FOR DETERMINING ANTIGENICALLY ACTIVE AMINO ACID SEQUENCES.
abstract A method of detecting or determining a sequence of amino acids which is antigenically active within a known amino acid sequence of a protein or portion thereof comprises the steps of: synthesising a plurality of peptides, each of said peptides comprising a sequence of a plurality of amino acids which corresponds to a sequence within the known amino acid sequence, and the said peptides having overlapping amino acid sequences; contacting each of said peptides with antibody against the protein or portion of interest; and detecting or determining the presence or absence of an antigen-antibody reaction between each of said peptides and said antibody to indicate whether or not said peptide has antigenic activity.
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