| abstract |
The invention provides 3-oxoisoindole compounds useful as diuretics of the general formulawherein X is halogen or trifluoromethyl, A is alkylene (C<sub>2</sub>-C<sub>4</sub>), R<sub>1</sub> is alkyl, R<sub>2</sub> is alkyl or phenylalkyl, or R<sub>1</sub> and R<sub>2</sub> taken together with nitrogen are piperidino, morpholino or pyridinyl. |