http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0136791-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S260-47 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1984-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1989-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0136791-B1 |
| titleOfInvention | Neocarzinostatin derivatives and method of producing the same |
| abstract | Neocarzinostatin derivatives, having anticancer activity. have the formula (A)wherein (NCS) represents a divalent neocarzinostatin residue in which a hydrogen atom is removed from each of the primary amino groups of the alanine residue at the N-terminal of neocarzinostatin and of the primary amino group of the lysine residue at the 20th position from the N-terminal of neocarzinostatin and (SMA) represents a monovalent partially half-esterified styrene-maleic acid copolymer residue having a weight-average molecular weight of 800 to 2,500 and consisting of structural units of(a) the styrene residue(b) the half-esterified maleic acid residuewherein R is an alcohol residue wherein the hydroxyl group has been removed from an alkanol having 1 to 4 carbon atoms, ethylene glycol monoalkyl ether in which the alkyl group has 1 or 2 carbon atoms or glycerine dialkyl ether wherein the alkyl group has 1 or 2 carbon atoms;(c) the maleic acid residueand(d) a residue having the following formula in which a hydroxyl group of one carboxyl group of a maleic acid residue has been removed to provide the link bonding the monovalent partially half-esterified styrene-maleic acid copolymer residue to the neocarzinostatin residue |
| priorityDate | 1983-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.