| abstract |
Compounds of the formula I <IMAGE> I where R1 is hydrogen, lower alkyl, lower alkoxy, amino or dialkylamino; R2 and R3 are O-alkyl, N-dialkyl or S-alkyl, or R2 and R3 together represent -X-(CH2)m-X, a carbonyl group or an imino group NR, and m is 2-6; where R4 is lower alkyl, cycloalkyl, alkenyl or dialkylamino, and where R5 is lower alkyl or cycloalkyl, and where n is 1 or 2, have excellent cytoprotective effects. They are prepared by reacting compounds II <IMAGE> II with formaldehyde or a reagent producing formaldehyde. |