| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 |
| filingDate |
1984-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44eb62dae42cce98175ac6fd69d2439f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22ac794b9a2ba1797bba5c6a08e06dc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42695e21c5daab6879ac1b2dec30f611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4988a4d031baebc4fee48c099c1d3668 |
| publicationDate |
1985-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0133308-A2 |
| titleOfInvention |
Agent for controlling the appetite and process for its preparation |
| abstract |
The invention relates to an appetite-regulating active substance and a method for producing the same, which is obtained from human and / or animal blood serum.n n n According to the invention, the blood serum is subjected to ultrafiltration, the filtrate is partially evaporated, then any proteins still in the filtrate are precipitated and centrifuged by adding trichloroacetic acid and the supernatant is purified by double gel filtration. The resulting active fractions are lyophilized.n n n The lyophilisate is dissolved in a weakly alkaline buffer and subjected to enzymatic decomposition by adding trypsin and chymotrypsin (0.01-0.2 parts of the enzyme per 1 part of lyophilisate). The mixture obtained is purified again by trichloroacetic acid. After the insoluble part has been separated off, the solution is subjected to a final gel chromatography (eluent: distilled water) and the active fractions are lyophilized.n n n The product obtained (Satietin-D) is a uniform glycoprotein that has an extremely strong appetite suppressant. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0271908-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0271908-A3 |
| priorityDate |
1983-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |