abstract |
A composition having an increased adriamycin or daunomycin activity and decreased toxicity prepared by mixing at least one compound selected from the group consisting of sulfites, acid sulfites, pyrosulfites, dithionites, and anhydrous sulfurous acid with adriamycin or daunomycin, and a method of administering adriamycin or daunomycin as a mixture with the above-described compound(s). The composition and the method make possible the use of adriamycin and daunomycin, which have serious adverse effects though they have remarkable activities, safely and effectively for treating various tumors. |