http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0128437-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-06
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-06
filingDate 1984-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a83c0edba43a9161ecc75068bef7125
publicationDate 1984-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0128437-A2
titleOfInvention Nortropine derivative, process for its preparation and its use
abstract The invention relates to the compound N-β-fluoroethylnortropine, which is suitable as an intermediate for the production of valuable pharmaceuticals (e.g. quaternary N-β-fluoroethylnortropine ester with spasmolytic and bronchospasmolytic activity) or as a pharmaceutical active substance.n n n This compound can be prepared, for example, by N-alkylation of nortropine with 2-bromofluoroethane.n n n Their acylation with benzilimidazolide leads to the benzilic acid N-β-fluoroethylnortropine ester, which in turn can be reacted with quaternizing agents to give the pharmacologically interesting quaternary benzilic acid N-β-fluoroethylnortropine esters.
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priorityDate 1983-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 27.