| abstract |
Process for the preparation of 1,1-disubstituted thioureas by reacting acid halides with isothiocyanates in the presence of organic solvents at a maximum of 15 ° C, then reacting the N-acylisothiocyanates thus formed with secondary amines at a temperature of at most 15 ° C for a maximum of 90 minutes and then for at least 180 minutes at a temperature of 20 to 35 ° C., separation of the organic solvents, addition of 5 to 38% by weight aqueous acids in a ratio of at most 4 equivalents of acid per mole of substance VI to the 1 thus formed, 1-disubstituted 3-acylthioureas and reaction of the mixture at a temperature of 20 to 100 ° C.n n n The 1,1-disubstituted thioureas which can be prepared by the process of the invention are valuable starting materials for the production of dyes, pharmaceuticals and pesticides. |