http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0126691-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81e318dacf701865f0ac54f3f912d0a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_925422dd1e5a8724f24c932c6bf62ec9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 |
| filingDate | 1984-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55114b208b7857f6958c74fb44736d9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c312b8037bc955410129ec9684884fcf |
| publicationDate | 1984-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0126691-A1 |
| titleOfInvention | Process for preparing a therapeutically useful extract from Brackenridgea zanguebarica, extract and such a medicine |
| abstract | 1° l'onsoumet les feuilles de Brackenridgeazanguebarica préalablement séchées et broyées à une extraction avec un solvant choisi parmi l'ensemble constitué parn a) l'acétone, b) les mélanges acétone-eau ayant un rapport volumique CH 3 COCH 3 -H 2 O supérieur ou égal à (3:7) v/v, et c) les mélanges alcool inférieur en C 1 -C 3 -eau ayant un rapport volumique alcool-eau compris entre (3:7) v/v et (1:1) v/v, nà une température comprise entre 45 et 60°C; 2° l'on soumet l'extrait ainsi obtenu à un traitement choisi parmi l'ensemble constitué parn a) l'extraction au moyen d'un solvant choisi parmi l'ensemble comprenant les hydrocarbures aliphatiques en C 1 -C 4 halogénés et leurs mélanges, pour extraire la substance active soluble dans ledit solvant et écarter la plus grande partie des substances indésirables non solubles dans ledit solvant; et b) le traitement au moyen d'un solvant choisi parmi l'ensemble comprenant les hydrocarbures aliphatiques en C 6 -C 7 , les hydrocarbures cycloaliphatiques en C 5 -C 6 , les hydrocarbures aromatiques et leurs mélanges, pour écarter la plus grande partie des substances indésirables solubles dans ledit solvant, la substance active n'étant pas soluble dans ledit solvant, et 3° l'on concentre le milieu liquide résultant à une température inférieure ou égale à 50°C sous pression réduite. The present invention relates to a process for the preparation of an extract of Brackenridgea zanguebarica comprising laséquoiaflavone useful in therapy. This process is characterized in that: 1 ° the leaves of the Brackenridgeazanguebarica are previously dried and ground to an extraction with a solvent chosen from the group consisting of a) acetone, b) acetone-water mixtures having a CH 3 COCH 3 -H 2 O volume ratio greater than or equal to (3: 7) v / v, and c) the lower C 1 -C 3 alcohol-water mixtures having an alcohol-water volume ratio of between (3: 7) v / v and (1: 1) v / v, at a temperature between 45 and 60 ° C; 2 ° the extract thus obtained is subjected to a treatment chosen from the group consisting of a) the extraction by means of a solvent chosen from the group comprising halogenated C 1 -C 4 aliphatic hydrocarbons and their mixtures, to extract the active substance soluble in said solvent and to remove most of the undesirable substances not soluble in said solvent; and b) treatment with a solvent chosen from the group comprising C 6 -C 7 aliphatic hydrocarbons, C 5 -C 6 cycloaliphatic hydrocarbons, aromatic hydrocarbons and their mixtures, to remove most of the undesirable substances soluble in said solvent, the active substance not being soluble in said solvent, and 3 ° the resulting liquid medium is concentrated at a temperature less than or equal to 50 ° C under reduced pressure. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7750052-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03062368-A1 |
| priorityDate | 1983-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.