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filingDate 1984-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1984-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0126351-A1
titleOfInvention Process for the isolation and purification of antibiotics
abstract A method for isolating and cleaning antibiotics is proposed in which an antibiotic-containing solution is extracted with an extractant at a temperature of 0 to 40 ° C. and a pressure which is between the critical pressure and ten times the critical pressure of the extractant is, the weight ratio of antibiotic solution to the extractant is 1: 5 to 1:20, in which the antibiotics are precipitated from the antibiotic-containing extractant by lowering its density and in which the extractant is circulated. An entrainer can be added to the extractant. The density of the extraction agent containing antibiotics can be reduced by relaxing to a pressure of 30 to 70 bar.
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