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filingDate 1984-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1984-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0124742-A2
titleOfInvention Process for the preparation of symmetric 1,4-dihydropyridine-carboxylic esters
abstract Process for the preparation of asymmetrical 1,4-dihydropyridines of the formula I <IMAGE>, where the radicals R1 and R2 are not identical, by reacting a ylidene compound of the formula II or III <IMAGE> with an enamine compound of the formula IV or V <IMAGE> characterized in that the ylidene compound of the formulas II or III by reacting a ketocarboxylic acid ester of the formulas VI or VII <IMAGE> with an aldehyde of the formula RCHO in a solvent in the presence of catalytic amounts of acetate salts of amines at temperatures of -10 ° C. and up 100 ° C manufactured.
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