| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7273 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D59-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-165 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D59-44 |
| filingDate |
1984-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc4301c12acd91fae8e2f352ef2c3ab9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e473217946b338eeb83711e83106ab3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d79bd8d57c1165f13a3c5d4267e5d5f |
| publicationDate |
1984-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0123552-A1 |
| titleOfInvention |
Method and apparatus for the mass spectrometric analysis of solutions |
| abstract |
An electrospray ion source for a mass spectrometer capable of generating ions from samples dissolved in a solution comprises a capillary tube (30) through which the said solution is pumped into a first chamber maintained substantially at atmospheric pressure and in which an inert gas, preferably heated, is flowing in a direction counter to the flow of the solution, and a small orifice (4) in the end wall (1) of the chamber opposite to and aligned with the capillary. A high potential difference is applied between the capillary tube (30) and the end wall (1) so thatthe solution is electrosprayed into the chamber and ions characteristic of the sample are formed. These ions are desolvated to a controllable extent by the inert gas, which is usually heated to improve the efficiency of the process and increase the maximum permissible flow rate of solution. The ions so formed pass through the small orifice (4) into a second chamber maintained at a reduced pressure, and into a mass spectrometer (29). Alternatively an additional pressure reduction stage can be included, so that the ions pass into a third chamber maintained at a still lower pressure in which the mass spectrometer (29) is situated through a hole (23) in skimmer (24). The ion source is particularly effective for the production of unfragmented and unsolvated ions from thermally unstable or involatile samples, and may be used as a liquid chromatograph - mass spectrometer interface. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61193062-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0260635-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0260635-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19652021-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8471200-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820980-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4885076-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4842701-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE34757-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19655304-B8
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113035686-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19655304-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113035686-A |
| priorityDate |
1983-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |