| abstract |
New benzobisoxazinetetrones having anti-allergic activity are described. These benzobisoxazinetetrones are represented by the following formula:n and pharmaceutically acceptable salts thereof, wherein:n X and Y are independently O, S, NH, N-alkyl or N-aryl; R 1 is H, lower alkyl, aryl, aralkyl, heterocyclic alkyl, alkoxyalkyl, aminoalkyl or carboxyalkyl; R 2 and R 3 are independently H, OH, alkoxy, lower alkyl, aryl, aralkyl, halogen,triffuoromethyl, nitro, cyano, carboxyor sulfonamido useful in the treatment of allergies. |