| abstract |
The compounds represented by the formula (I)n wherein m is 0, 1 or 2; p is 9, 10. 11, 12 or 13; R, is hvdrogen, amino orn R 2 is hydroxyl, amino,n -NHCH 2 CONH 2 ; and X is -CO 2 H,n orn wherein n is 1 or 2, Y is hydrogen or hydroxyl or amino with the proviso that when m is 0, R 1 is hyrogen, or pharmaceutically acceptable salt thereof have been found to be leukotriene antagonists and useful in the treatment of diseases in which leukotrienes are a factor, such as asthma. |