http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0119431-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f71a1da2008f53a16ba311fa193570cf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 1984-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7701a6de5ce384c92d12e9a0d2189afa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1307b051f45ba71f2d65000d4406f6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46b32d31ab3efd97cadbf4c5ea90fd3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed25406a4d723ea1074bc9f307d27a53 |
| publicationDate | 1984-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0119431-A1 |
| titleOfInvention | Method of preparing erythromycin A cyclic 11,12-carbonate |
| abstract | The invention solves the problem of the industrial method of production of erythromycin A cyclic 11,12-carbonate by transesterification of 1,2-diole or 1,3-diole carbonates by means of anhydrous erythromycin A or its salts in anhydrous organic solvents or in the medium of a transesterified substrate in the presence of a phase transfer catalyst (PTC). n According to the invention quarternary ammonium and phosphonium compounds may be used in the transesterification process with addition of inorganic compounds, such as salts, alkali metal or alkaline earth metal oxides or hydroxides. Ammonium or phosphonium hydroxides or carbonates do not require any addition of inorganic compounds. n According to the invention, as catalysts of the PTC type there may also be used coronary ethers and cryptands with addition of inorganic compounds. n As quarternary ammonium compounds there are used salts, such as triethylbenzylammonium (TEBA) chloride or carbonate, tetrabutylammonium bromide, trioctylmethylammonium chloride, whereas among phosphonium compounds there are advantageously used tetrabutylphosphonium chloride or carbonate. Among crown ethers there n is used 1,4,7,10,13,16-hexaoxacyclo-octadecane and among cryptands 4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8,8,8]-hexacosane. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2677025-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2680790-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102377-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0487411-A1 |
| priorityDate | 1983-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.