http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0119161-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0222 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate | 1984-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8584d3db842a644949a7280fe03ce66 |
publicationDate | 1984-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0119161-A2 |
titleOfInvention | Benzazocinone and benzazoninone derivatives, process for their preparation, pharmaceutical preparations containing these compounds, and their therapeutical use |
abstract | The invention relates to inhibitors of the angiotensin converting enzyme of the formula wherein R A and R B are radicals of the formula represent wherein R ° represents carboxy or a functionally modified carboxy; R 1 is hydrogen, lower alkyl, amino-lower alkyl, aryl, aryl-lower alkyl, cycloalkyl, cycloalkyl-lower alkyl, acylamino-lower alkyl, mono- or di-lower alkylamino-lower alkyl, lower alkylthio-lower alkyl, carboxy-lower alkyl, esterified carboxy-lower alkyl, carbamoyl- lower alkyl, N-substituted carbamoyl lower alkyl, hydroxy lower alkyl, etherified or acylated hydroxy lower alkyl, aryloxy lower alkyl, aryl (thio, sulfinyl or sulfonyl) lower alkyl, aryl-N-lower alkylamino lower alkyl or arylamino lower alkyl means; R 2 represents hydrogen or lower alkyl; R 3 and R 4 are independently hydrogen, lower alkyl, lower alkoxy, lower alkanoyloxy, hydroxy, halogen or trifluoromethyl, or R 3 and R 4 together represent lower alkylene dioxy; R 5 represents hydrogen or lower alkyl; m represents 2 or 3; and X represents oxo, two hydrogen atoms or hydroxy or acylated hydroxy together with a hydrogen atom; and wherein the carbocyclic ring can also be hexahydro; Salts and stereoisomers of all of these compounds; Process for their preparation, pharmaceutical preparations containing these compounds, and their therapeutic use. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0166357-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0166357-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0166354-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011110277-A1 |
priorityDate | 1983-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 464.