http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0118848-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D457-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-48 |
filingDate | 1984-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1992-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1992-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0118848-B1 |
titleOfInvention | Ergoline derivatives, process for their preparation and their pharmaceutical application |
abstract | Substituted ergolines of the formula <IMAGE> and their acid addition salts, wherein the urea side chain in the 8-position can be in the d alpha - or beta -configuration, C2 C3 and C9 C10 are a CC single or C=C double bond, and R is hydrogen or NR'R'' wherein R'R'' is O2, H2, C1-4-dialkyl, or, together, they form a 3- to 9-membered ring, or R' and R'' individually are hydrogen, C1-4-alkyl, or C1-10--acyl, R1 is hydrogen, C1-4-alkyl, C1-10-acyl, C6-8-aryl, or C1-4-alkylsulfonyl, R2 is hydrogen or halogen if C2 C3 is a C=C double bond, or hydrogen if C2 C3 is a CC single bond, R6 is C1-4-alkyl, show a pronounced effect on the central nervous system and are suitable, for example, as antidepressants, neuroleptics, or antihypertensives. |
priorityDate | 1983-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.