| abstract |
Cephalosporin compounds represented by the general formula (I), wherein R' represents alkyl, alkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylmethyl, or substituted phenoxymethyl, and R 2 represents carboxyl or protected carboxyl, are prepared in a high yield with a high purity by reacting a thiazolinoazetidinone derivative represented by the general formula (II), with successively, a nucleophilic agent, a sulfur-containing compound, and ammonia. |