http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0116431-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-26 |
| filingDate | 1984-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b9e80789ecf1dcf83d8d470a2f8b7f |
| publicationDate | 1984-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0116431-A1 |
| titleOfInvention | Aromatase inhibiting pyrimidine derivatives |
| abstract | Pyrimidine derivatives of the formulan or a pharmaceutically acceptable salt thereof, wherein R isn 2-chloroethyl, C 3 -C 8 cycloalkyl, phenoxy-substituted C 1 -C 4 alkyl, or norbornan-2-yl.n R 1 is methyl, trifluoromethyl, methoxy, fluoro, chloro, bromo, or nitro; R 2 is hydrogen, methyl, trifluoromethyl, methoxy, fluoro, chloro, bromo, or nitro; each of R 3 and R 4 is independently hydrogen, methyl, methoxy, fluoro, or chloro; and X is hydrogen, hydroxy, methyl, or halo, with the proviso that if R, is methoxy, R must be substituted phenyl with at least one of R 3 and R 4 being other than hydrogen inhibit aromatase and are useful in treating or preventing estrogen-dependent diseases in mammals. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0165779-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0165777-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0354689-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0240263-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0240263-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4769378-A |
| priorityDate | 1983-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 155.