http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0115314-B1

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filingDate 1984-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1988-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1988-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0115314-B1
titleOfInvention Process for the preparation of cholecalciferol derivatives
abstract for the Contracting States BE, CH, DE, FR, GB, IT, LI, NL 1. A process for the manufacture of 1 alpha,23(R),25-trihydroxycholecalciferol of the formula see diagramm : EP0115314,P14,F1 characterized by a) reacting a compound of the formula see diagramm : EP0115314,P15,F2 wherein R**1 and R**2 are hydrogen, lower alkyl or aryl or together are C3 -6 -alkylene, with a compound of the formula see diagramm : EP0115314,P15,F3 Wherein R**3 is lower alkyl or aryl, to give a compound of the formula see diagramm : EP0115314,P15,F4 wherein R**1, R**2 and R**3 have the above significance, and b) cleaving off the protecting groups from the compound of formula IV. For the contracting state AT 1. A process for the manufacture of 1 alpha,23(R),25-trihydroxycholecalciferol of the formula see diagramm : EP0115314,P16,F1 characterized by a) reacting a compound of the formula see diagramm : EP0115314,P17,F2 wherein R**1 and R**2 are hydrogen, lower alkyl or aryl or together are C3 -6 -alkylene, with a compound of the formula see diagramm : EP0115314,P17,F3 Wherein R**3 is lower alkyl or aryl, to give a compound of the formula see diagramm : EP0115314,P17,F4 wherein R**1, R**2 and R**3 have the above significance, and b) cleaving off the protecting groups from the compound of formula IV.
priorityDate 1983-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 55.